Zhonghua nei ke za zhi · 2002
[Diaphragmatic motor evoked potential in amyotrophic lateral sclerosis patients].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Zhuang Li, Tang Xiaofu, Fan Dongsheng, Xu Xianhao, Li Benhong, Du Hua, Jiang Jingwen
Аннотация
OBJECTIVE: To investigate the features and application of diaphragmatic motor evoked potential (DMEP) in amyotrophic lateral sclerosis (ALS) patients.
METHODS: To record the latency and amplitude of diaphragmatic compound muscle action potential (DCMAP) from 37 ALS patients and 31 control subjects with surface electrodes after transcranial and transcervical magnetic stimulation, central motor conduction time (CMCT) was calculated. The percentage of forced vital capacity (%FVC) was performed in 22 ALS patients simultaneously.
RESULTS: Cortical and cervical latencies of the ALS patients were longer than those of the controls, and cortical and cervical amplitudes of the ALS patients were lower than those of the controls. CMCT of the ALS patients were longer than that of the controls. Cortical latency, cortical amplitude and CMCT were all correlated with the dysfunction of the pyramidal tract. Cortical latency and CMCT were also correlated with the clinical respiratory dysfunction, cervical latency was correlated with %FVC.
CONCLUSIONS: CMCT, Cortical and cervical latencies are sensitive index in DMEP parameters reflecting respiratory dysfunction in ALS, CMCT reflects cortical spinal tract function of ALS patients associated with respiration. It would be helpful to detect the neurological basis of the respiratory disturbance in ALS combining CMCT with cervical latency.
METHODS: To record the latency and amplitude of diaphragmatic compound muscle action potential (DCMAP) from 37 ALS patients and 31 control subjects with surface electrodes after transcranial and transcervical magnetic stimulation, central motor conduction time (CMCT) was calculated. The percentage of forced vital capacity (%FVC) was performed in 22 ALS patients simultaneously.
RESULTS: Cortical and cervical latencies of the ALS patients were longer than those of the controls, and cortical and cervical amplitudes of the ALS patients were lower than those of the controls. CMCT of the ALS patients were longer than that of the controls. Cortical latency, cortical amplitude and CMCT were all correlated with the dysfunction of the pyramidal tract. Cortical latency and CMCT were also correlated with the clinical respiratory dysfunction, cervical latency was correlated with %FVC.
CONCLUSIONS: CMCT, Cortical and cervical latencies are sensitive index in DMEP parameters reflecting respiratory dysfunction in ALS, CMCT reflects cortical spinal tract function of ALS patients associated with respiration. It would be helpful to detect the neurological basis of the respiratory disturbance in ALS combining CMCT with cervical latency.