Evaluation of captopril renography with 99mTc-MAG3 in the diagnosis of renovascular hypertension.

Eighty-one patients with suspected renovascular hypertension (RVH) were studied using 99mTc-MAG3 renography before and after administration of 25 mg captopril (CAP). Among the 81 cases, 22 were proven by renal arteriography or DSA. The results showed that by using CAP, the sensitivity and specificity of renography in RVH diagnosis increased from 66% to 72% and from 33% to 100%, respectively. We conclude that renography is a simple, noninvasive, sensitive and specific method for screening RVH and is suitable for use in hospitals with no gamma-cameras.