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Войти в исследования Dermatology (Basel, Switzerland) · 2009
Tolerance of oat-based topical products in cereal-sensitized adults with atopic dermatitis.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Goujon Catherine, Jean-Decoster Catherine, Dahel Karima, Bottigioli David, Lahbari Farida, Nicolas Jean-François, Schmitt Anne-Marie
Аннотация
BACKGROUND: Few data suggest oat-based cosmetics may cause allergic reactions in atopic subjects, especially when sensitized to cereals.
OBJECTIVES: To evaluate the risk of immediate and delayed allergic reactions to repeated and maximized applications (RMA) of oat-containing cosmetics and oat extracts and their tolerance in cereal-sensitized atopic adults.
METHODS: Open-label pilot study in 12 cereal-sensitized atopic adults over 45 days. Open tests and RMA were performed with Rhealba oat-containing cosmetics at day 0 (D0) and D10, and from D10 to D31. Patch and prick tests were performed at D7 and D42 with wheat and Rhealba oat extracts and the study cream.
RESULTS: The RMA of oat-based cosmetics in cereal-sensitized atopic adults did not induce any immediate or delayed allergic reaction and was well tolerated. No immediate or delayed positive skin test to oat extracts was observed.
CONCLUSION: Sensitization to cereals does not increase the risk of allergic reactions to oat-containing cosmetics.
OBJECTIVES: To evaluate the risk of immediate and delayed allergic reactions to repeated and maximized applications (RMA) of oat-containing cosmetics and oat extracts and their tolerance in cereal-sensitized atopic adults.
METHODS: Open-label pilot study in 12 cereal-sensitized atopic adults over 45 days. Open tests and RMA were performed with Rhealba oat-containing cosmetics at day 0 (D0) and D10, and from D10 to D31. Patch and prick tests were performed at D7 and D42 with wheat and Rhealba oat extracts and the study cream.
RESULTS: The RMA of oat-based cosmetics in cereal-sensitized atopic adults did not induce any immediate or delayed allergic reaction and was well tolerated. No immediate or delayed positive skin test to oat extracts was observed.
CONCLUSION: Sensitization to cereals does not increase the risk of allergic reactions to oat-containing cosmetics.