Contact dermatitis · 2018
European Surveillance System on Contact Allergies (ESSCA): polysensitization, 2009-2014.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Dittmar Daan, Uter Wolfgang, Bauer Andrea, Fortina Ana B, Bircher Andreas J, Czarnecka-Operacz Magdalena, Dugonik Aleksandra, Elsner Peter, Gallo Rosella, Ghaffar Sharizan A, Giménez-Arnau Anna, Johnston Graham A, Kręcisz Beata, Filon Francesca L, Rustemeyer Thomas, Sadowska-Przytocka Anna, Sánchez-Pérez Javier, Schnuch Axel, Simon Dagmar, Spiewak Radoslaw, Spring Philipp, Corradin Maria T, Valiukevičienė Skaidra, Vok Marko, Weisshaar Elke, Wilkinson Mark, Schuttelaar Marie L, ESSCA Network
Аннотация
BACKGROUND: Polysensitization, defined as being allergic to three or more haptens from the European baseline series, is considered to reflect increased susceptibility to developing a contact allergy, and is likely to be associated with an impaired quality of life.
OBJECTIVES: To evaluate the prevalences of polysensitization across Europe and to analyse factors associated with polysensitization.
METHODS: Patch test data collected by the European Surveillance System on Contact Allergies (ESSCA; www.essca-dc.org) in consecutively patch tested patients from January 2009 to December 2014, comprising 11 countries and 57 departments, were retrospectively analysed.
RESULTS: A total of 86 416 patients were available for analysis, showing a standardized prevalence of polysensitization of 7.02%, ranging from 12.7% (Austria) to 4.6% (Italy). Allergen pairs with the strongest association are reported for the total population, for South Europe, and for North/Central Europe. Overall, polysensitized patients showed a higher percentage of extreme (+++) positive patch test reactions than oligosensitized patients. Female sex, occupational dermatitis and age > 40 years were risk factors for polysensitization.
CONCLUSIONS: The varying prevalences of polysensitization across Europe most likely reflect differences in patient characteristics and referral patterns between departments. Known risk factors for polysensitization are confirmed in a European dermatitis population.
OBJECTIVES: To evaluate the prevalences of polysensitization across Europe and to analyse factors associated with polysensitization.
METHODS: Patch test data collected by the European Surveillance System on Contact Allergies (ESSCA; www.essca-dc.org) in consecutively patch tested patients from January 2009 to December 2014, comprising 11 countries and 57 departments, were retrospectively analysed.
RESULTS: A total of 86 416 patients were available for analysis, showing a standardized prevalence of polysensitization of 7.02%, ranging from 12.7% (Austria) to 4.6% (Italy). Allergen pairs with the strongest association are reported for the total population, for South Europe, and for North/Central Europe. Overall, polysensitized patients showed a higher percentage of extreme (+++) positive patch test reactions than oligosensitized patients. Female sex, occupational dermatitis and age > 40 years were risk factors for polysensitization.
CONCLUSIONS: The varying prevalences of polysensitization across Europe most likely reflect differences in patient characteristics and referral patterns between departments. Known risk factors for polysensitization are confirmed in a European dermatitis population.