Pakistan journal of medical sciences · 2026
Comparison of outcomes of extracorporeal shock wave lithotripsy versus retrograde intrarenal surgery in the management of renal calculi measuring one to two centimeters.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Arshad Muhammad Waqas, Javed Atif, Ahadi Shafeullah, Ghayoor Yousaf Azhar
Аннотация
OBJECTIVES: To compare outcomes of extracorporeal shock wave lithotripsy (ESWL) and retrograde intrarenal surgery (RIRS) for renal stones measuring 1-2 cm, including stone clearance, hospital stay, hematuria, sepsis, postoperative pain, and retreatment.
METHODOLOGY: Six months, single-center, open-label, parallel-group randomized controlled trial was conducted at the Department of Urology, Dr. Ziauddin Hospital, North Nazimabad, Karachi, from September 5, 2025 to March 4, 2026. Ninety-eight eligible adults were enrolled consecutively and randomized 1:1 to ESWL or RIRS by lottery method using concealed identical allocation slips. Non-contrast CT-KUB was performed at baseline and at 28 days. Pain was assessed by VAS at 24 hours. Data were analyzed using SPSS version 26, with p<0.05 considered significant.
RESULTS: Baseline characteristics were comparable between the treatment groups. Stone-free status after one session was 53.1% with ESWL and 85.7% with RIRS (RR 1.62, 95% CI 1.21 to 2.15; p<0.001), while 28-day stone clearance was 67.3% and 85.7%, respectively (RR 1.27, 95% CI 1.02 to 1.60; p=0.032). ESWL was associated with shorter hospital stay (p<0.001). Median VAS pain score at 24 hours was higher after ESWL [4 (IQR 3-4)] than RIRS [3 (IQR 2-4); p<0.001]. Retreatment was more frequent after ESWL (30.6% vs 10.2%; RR for RIRS vs ESWL 0.33, 95% CI 0.13 to 0.85; p=0.012), while gross hematuria and postoperative sepsis were comparable.
CONCLUSION: RIRS provided higher clearance and lower retreatment and pain scores than ESWL, while ESWL was associated with shorter hospital stay. Registration Number: www. clinicaltrials.gov (NCT07261995).
METHODOLOGY: Six months, single-center, open-label, parallel-group randomized controlled trial was conducted at the Department of Urology, Dr. Ziauddin Hospital, North Nazimabad, Karachi, from September 5, 2025 to March 4, 2026. Ninety-eight eligible adults were enrolled consecutively and randomized 1:1 to ESWL or RIRS by lottery method using concealed identical allocation slips. Non-contrast CT-KUB was performed at baseline and at 28 days. Pain was assessed by VAS at 24 hours. Data were analyzed using SPSS version 26, with p<0.05 considered significant.
RESULTS: Baseline characteristics were comparable between the treatment groups. Stone-free status after one session was 53.1% with ESWL and 85.7% with RIRS (RR 1.62, 95% CI 1.21 to 2.15; p<0.001), while 28-day stone clearance was 67.3% and 85.7%, respectively (RR 1.27, 95% CI 1.02 to 1.60; p=0.032). ESWL was associated with shorter hospital stay (p<0.001). Median VAS pain score at 24 hours was higher after ESWL [4 (IQR 3-4)] than RIRS [3 (IQR 2-4); p<0.001]. Retreatment was more frequent after ESWL (30.6% vs 10.2%; RR for RIRS vs ESWL 0.33, 95% CI 0.13 to 0.85; p=0.012), while gross hematuria and postoperative sepsis were comparable.
CONCLUSION: RIRS provided higher clearance and lower retreatment and pain scores than ESWL, while ESWL was associated with shorter hospital stay. Registration Number: www. clinicaltrials.gov (NCT07261995).