Gan to kagaku ryoho. Cancer & chemotherapy · 2016
[Pathological Complete Response Obtained by Eribulin Chemotherapy in a Case of Advanced Breast Cancer].
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Asano Yuka, Kashiwagi Shinichiro, Goto Wataru, Takada Koji, Morisaki Tamami, Takashima Tsutomu, Noda Satoru, Onoda Naoyoshi, Ohsawa Masahiko, Hirakawa Kosei, Ohira Masaichi
Аннотация
A goal for treating advanced disease is prolonging survival while maintaining a good quality of life(QOL). Eribulin chemotherapy may be suitable for this purpose. We report a case of advanced breast cancer with pathological complete response (pCR)obtained by eribulin chemotherapy. The patient was a 43-year-old woman who complained of a right mammary mass. A tumor measuring approximately 3 cm was palpated, and breast cancer was detected via ultrasound examination. Core needle biopsy indicated invasive ductal carcinoma based on histopathological findings. A metastasis to the supraclavicular lymph node was observed and was found to be malignant via fine-needle aspiration cytology. The patient was diagnosed with advanced breast cancer cT2N3M0, stage III C, Luminal B like. She underwent primary systemic therapy with 6 cycles of eribulin. The patient exhibited a clinical complete response to eribulin chemotherapy. Thereafter, a right mastectomy with level 3 axillary lymph node dissection was performed. Pathological diagnosis of the surgical specimen was pCR. At present, 3 years after surgery, the patient has no recurrence.