Cost-effectiveness of the adherence with recommendations for clinical monitoring of patients with diabetes.
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Corrao Giovanni, Rea Federico, Mancia Giuseppe, Perseghin Gianluca, Merlino Luca, Martini Nello, Carbone Simona, Carle Flavia, working group “Monitoring and assessing diagnostic-therapeutic paths (MAP)” of the Italian Ministry of Health, Polytechnic University of Marche (coordinator), Italian Ministry of Health, Dept of Health Planning, Dept of health prevention, University of Milano-Bicocca, Laboratory of Healthcare Research & Pharmacoepidemiology, Department of Epidemiology Lazio Region, Aosta Valley Region, Campania Region, Emilia Romagna Region, Friuli Venezia Giulia Region, Lazio Region, Lombardy Region, Marche Region, Molise Region, Puglia Region, Sicily Region, Tuscany Region, Veneto Region, Research and Health Foundation (Fondazione ReS -Ricerca e Salute-), National Agency for Regional Health Services, ANMCO (National Association of Hospital Cardiologists) Study Center
Аннотация
METHODS AND RESULTS: A population-based cohort study was carried out by including the 20,635 patients, residents in the Lombardy Region (Italy), who in the year 2012 were newly taken-in-care for diabetes. Adherence with clinical recommendations (i.e., controls for glycated haemoglobin, lipid profile, urine albumin excretion and serum creatinine) was recorded during the first year after the patient was taken-in-care, and categorized according whether he/she complied with none or almost none (0 or 1), just some (2) or all or almost all (3 or 4) the recommendations, respectively denoted as poor, intermediate and high adherence. Short- and long-term complications of diabetes, and healthcare cost incurred by the National Health Service, were assessed during follow-up. Compared with patients with poor adherence, those with intermediate and high adherence respectively showed (i) a delay in outcome occurrence of 13 days (95% CI, -2 to 27) and 23 days (9-38), and (ii) a lower healthcare cost of 54 € and 77 €. In average, a gain of 18 Euros and 15 Euros for each day free from diabetic complication by increasing adherence respectively from poor to intermediate and from poor to high were observed.
CONCLUSION: Close control of patients with diabetes through regular clinical examinations must be considered the cornerstone of national guidance, national audits, and quality improvement incentive schemes.