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HPB : the official journal of the International Hepato Pancreato Biliary Association · 2026

Incidence, timing, risk factors, and outcomes of unplanned reintubation after liver and pancreatic resection.

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Alizai Qaidar, Chatzipanagiotou Odysseas P, Mevawalla Areesh, Angez Meher, Elemosho Abdulaziz, Ejaz Rida, Pawlik Timothy M

Аннотация

BACKGROUND: Unplanned postoperative reintubation (UPR) may be associated with subsequent complications and increased mortality. We sought to characterize risk factors and outcomes associated with UPR after liver or pancreatic resections.

METHODS: Adult patients who underwent elective liver or pancreatic surgery were identified in the National Surgical Quality Improvement Project Database (2014-2021). Univariate and multivariable regression analyses were conducted.

RESULTS: Among 85,077 patients (liver = 34,892, pancreas = 50,185), 2.3 % (n = 1929) individuals required UPR with a median time to reintubation of 5 days (IQR 2-10). On multivariable regression, risk factors associated with UPR after liver resection included age ≥80 years (aOR = 4.24, 95%CI [2.81-6.38]) and total right lobectomy (aOR = 1.69, 95%CI [1.35-2.13]) while in the pancreatic surgery cohort, the risk factors included Whipple procedure (aOR = 1.64, 95%CI [1.40-1.92]) and pancreatic fistula (aOR = 2.50, 95%CI [2.11-2.97]). UPR was strongly associated with longer LOS (Liver∼+8.00 days; Pancreas∼+6.33 days) and 30-day mortality (aOR, Liver = 38.26; Pancreas = 17.38).

CONCLUSION: UPR occurred in ∼2 % of patients after liver and pancreatic resection. Risk factors and outcomes differed by organ, but UPR consistently marked severe postoperative deterioration substantially high mortality.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты