Acta neurochirurgica. Supplement · 2006
First clinical experiences in patients with idiopathic normal-pressure hydrocephalus with the adjustable gravity valve manufactured by Aesculap (proGAV(Aesculap)).
Клиническое исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Meier U, Lemcke J
Аннотация
OBJECTIVE: Improved clinical outcomes after implantation of a low pressure valve in patients with idiopathic normal-pressure hydrocephalus is usually achieved at the expense of a higher overdrainage rate. Can an adjustable valve with a gravitational unit provide optimal results?
METHOD: In a prospective clinical outcome study conducted in the Unfallkrankenhaus Berlin, 30 patients with idiopathic normal-pressure hydrocephalus were treated surgically between June 2004 and May 2005 with the valve combination described above, and reexamination 3 months or 6 months postoperatively.
RESULTS: Clinical outcome correlates with opening pressure level of the valve. Controlled adjustment of the valve from 100 mmH2O to 70 mmH2O, and then to 50 mmH2O after 3 months, permits optimum adaptation of the brain to the implanted valve without overdrainage complications.
CONCLUSIONS: Advantages of this programmable gravity valve include: 1) the absence of unintentional readjustment through external magnets, and 2) the possibility of controlling the valve setting using an accessory instrument without the need for x-ray monitoring. A significant disadvantage is adjusting the valve after implantation. From the clinical point of view, this new "proGAV(Aesculap)" valve is a necessary development in the right direction, but at the moment it is still beset with technical problems.
METHOD: In a prospective clinical outcome study conducted in the Unfallkrankenhaus Berlin, 30 patients with idiopathic normal-pressure hydrocephalus were treated surgically between June 2004 and May 2005 with the valve combination described above, and reexamination 3 months or 6 months postoperatively.
RESULTS: Clinical outcome correlates with opening pressure level of the valve. Controlled adjustment of the valve from 100 mmH2O to 70 mmH2O, and then to 50 mmH2O after 3 months, permits optimum adaptation of the brain to the implanted valve without overdrainage complications.
CONCLUSIONS: Advantages of this programmable gravity valve include: 1) the absence of unintentional readjustment through external magnets, and 2) the possibility of controlling the valve setting using an accessory instrument without the need for x-ray monitoring. A significant disadvantage is adjusting the valve after implantation. From the clinical point of view, this new "proGAV(Aesculap)" valve is a necessary development in the right direction, but at the moment it is still beset with technical problems.