Nippon Ganka Gakkai zasshi · 2013
[Clinical course of retinopathy of prematurity and other neonatal complications in Kobe Children's Hospital].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Shimoyama Tsuyoshi, Yokoyama Tomoko, Nomura Koji
Аннотация
PURPOSE: To report changes in retinopathy of prematurity (ROP) and other neonatal complications for the last 15 years
CASES AND METHOD: 638 cases with a birth weight of less than 1000 g were categorized into two groups in oxygen management changes based on reduced oxygen protocol before and after change (Group A: 218 cases from 1997 to 2001, Group B: 420 cases from 2002 to 2011). Prematurity and the clinical course of ROP were reviewed. In addition, the incidence of 5 main neonatal complications before and after oxygen control criterion change was compared.
RESULTS: The differences in birth weight and gestational age among the two groups were not significant (A: 765 138 g/26.5 +/- 2.2 weeks, B: 753 +/- 158 g/26.1 +/- 2.3 weeks). The incidence of ROP and the rate of treatment for ROP in Group B were significantly less than in Group A (A: 83.0%/32.6% VS B: 54.8%/ 10.0%; p < 0.01). The rate of forming a cicatricial phase severer than grade 3 was 4.1% in Group A and 1.7% in Group B (p = 0.06). The incidence of neonatal complications before and after oxygen management change was not significantly different.
CONCLUSION: Incidence and treatment of ROP were improved after changing to the reduced oxygen protocol. There was no increase in neonatal complications after the management change.
CASES AND METHOD: 638 cases with a birth weight of less than 1000 g were categorized into two groups in oxygen management changes based on reduced oxygen protocol before and after change (Group A: 218 cases from 1997 to 2001, Group B: 420 cases from 2002 to 2011). Prematurity and the clinical course of ROP were reviewed. In addition, the incidence of 5 main neonatal complications before and after oxygen control criterion change was compared.
RESULTS: The differences in birth weight and gestational age among the two groups were not significant (A: 765 138 g/26.5 +/- 2.2 weeks, B: 753 +/- 158 g/26.1 +/- 2.3 weeks). The incidence of ROP and the rate of treatment for ROP in Group B were significantly less than in Group A (A: 83.0%/32.6% VS B: 54.8%/ 10.0%; p < 0.01). The rate of forming a cicatricial phase severer than grade 3 was 4.1% in Group A and 1.7% in Group B (p = 0.06). The incidence of neonatal complications before and after oxygen management change was not significantly different.
CONCLUSION: Incidence and treatment of ROP were improved after changing to the reduced oxygen protocol. There was no increase in neonatal complications after the management change.