[The characteristics of prostaglandin and cyclic nucleotide biosynthesis in patients with peptic ulcer and chronic atrophic gastritis during digestion].

Prostaglandins (PG) and cyclic nucleotides (CN) were assessed radioimmunologically in the blood plasma under basal conditions and after a standard breakfast in 20 patients with duodenal ulcer, 16--with gastric body ulcer and 18 patients with atrophic gastritis. It was established that the patients showed an increased PG level, cAMP-dependent processes. Neurohumoral mechanisms of regulation of gastric secretion were abnormal.