Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021
Second-generation sequencing assistance in the diagnosis of Pasteurella multocida empyema: A case report.
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Liu Bin, Huang Peng, Liu Shuangbo, Liang Yanchao, Chen Fangwei, Quan Lingli, Luo Xiping, Zhou Juan
Аннотация
Pasteurella multocida empyema is rare and easy to be misdiagnosed. An 81-year-old male patient showed symptoms with cough, sputum, and fever for 3 days. Community-acquired pneumonia was diagnosed firstly. After anti-infection treatment, the patient was still in fever. Chest radiography showed pleural effusion, closed thoracic drainage was performed and the reddish-brown fluid was drained out. The second-generation sequencing was performed on pleural fluid and Pasteurella multocida was detected. Pasteurella multocida has strict requirements for growth conditions and it difficult to cultivate. The application of second-generation sequencing is helpful to diagnose the pathogen rapidly.