Sarcoidosis-like reaction related to Propionibacterium acnes and immune restoration syndrome in HIV infection .

Propionibacterium acnes is thought to be a potential triggering agent of sarcoidosis. We describe a woman who developed chronic meningitis with sarcoid-like multisystemic involvement under treatment for human immunodeficiency virus infection. P. acnes was isolated from cerebrospinal fluid. We assume that P. acnes might have triggered this sarcoid-like reaction with meningitis, as a consequence of an immune reconstitution.