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Войти в исследования Impact of Proportionality of Secondary Tricuspid Regurgitation on Outcomes After Tricuspid Transcatheter Edge-to-Edge Repair.
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Russo Giulio, Pedicino Daniela, Adamo Marianna, Alessandrini Hannes, Andreas Martin, Braun Daniel, Connelly Kim A, Denti Paolo, Estevez-Loureiro Rodrigo, Fam Neil, Hahn Rebecca T, Harr Claudia, Hausleiter Joerg, Kalbacher Daniel, Ho Edwin, Latib Azeem, Lubos Edith, Ludwig Sebastian, Lurz Philipp, Metra Marco, Monivas Vanessa, Nickenig Georg, Pedrazzini Giovanni, Pozzoli Alberto, Praz Fabien, Rodes-Cabau Josep, Besler Christian, Rommel Karl-Philipp, Schofer Joachim, Scotti Andrea, Lentini Nicolò, Pastorino Roberta, Piayda Kerstin, Sievert Horst, Tang Gilbert H L, Pascual Isaac, Thiele Holger, Schlotter Florian, Sangiorgi Giuseppe Massimo, von Bardeleben Ralph Stephan, Webb John, Windecker Stephan, Leon Martin, Enriquez-Sarano Maurice, Maisano Francesco, Bloechlinger Stefan, Taramasso Maurizio
Аннотация
METHODS: Patients undergoing tricuspid transcatheter edge-to-edge repair were selected from the TRIVALVE registry (International Multisite Transcatheter Tricuspid Valve Therapies Registry). Patients were divided according to the ratio between effective regurgitant orifice area (EROA) and right ventricular (RV) end diastolic diameter (RVEDD) into tertiles: patients with low EROA/RVEDD (RV, dominant); intermediate EROA/RVEDD (RV and TR, RV-TR, codominant), and high EROA/RVEDD (TR, dominant). The primary outcome was all-cause mortality. Median follow-up was 9.7 months (4.2-12.0).
RESULTS: A total of 204 patients were included in the present study: 67 for the RV dominant, 68 for the RV-TR codominant, and 69 for the TR dominant group. The 3 groups presented different baseline characteristics. Survival analysis among the 3 groups showed a trend towards worse prognosis for the RV-dominant group, as compared with the RV-TR codominant and TR dominant groups.
CONCLUSIONS: The conceptual framework of proportionality is applicable to TR with EROA/RVEDD, defining a higher risk RV-dominant phenotype with a trend towards worse survival after tricuspid transcatheter edge-to-edge repair.