Gastrointestinal endoscopy · 2024
Distal cap-assisted EMR allows the safe and effective resection of adherent dysplastic lesions in the setting of inflammatory bowel disease: a multicenter retrospective study (with video).
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Moyer Matthew T, Leisgang Allison R, Kelly Melissa, Rex Douglas K
Аннотация
BACKGROUND AND AIMS: EMR is established as the primary approach for large and complex dysplastic lesions. However, submucosal fibrosis caused by previous attempts at removal, biopsy sampling, inflammation, or tattoo placement can cause a benign "negative lift sign" and create difficulty for EMR. Here, we present the use of distal cap-assisted EMR (EMR-DC) specifically for the use of resecting dysplastic colonic lesions when submucosal fibrosis is present in patients with inflammatory bowel disease (IBD).
METHODS: Sixteen IBD patients were retrospectively evaluated from 2 high-volume centers. Patient demographics, lesion pathology and classification, outcomes including time and success of resection, serious adverse events (SAEs) within 30 days of the procedure, and efficacy were measured.
RESULTS: Seventy-five percent of patients treated with EMR-DC achieved complete resection with no SAEs within 30 days of the procedure.
CONCLUSIONS: EMR-DC represents an attractive option for the resection of adherent, dysplastic lesions in chronic IBD that is effective, safe, and inexpensive.
METHODS: Sixteen IBD patients were retrospectively evaluated from 2 high-volume centers. Patient demographics, lesion pathology and classification, outcomes including time and success of resection, serious adverse events (SAEs) within 30 days of the procedure, and efficacy were measured.
RESULTS: Seventy-five percent of patients treated with EMR-DC achieved complete resection with no SAEs within 30 days of the procedure.
CONCLUSIONS: EMR-DC represents an attractive option for the resection of adherent, dysplastic lesions in chronic IBD that is effective, safe, and inexpensive.