An example of the use of quantitation in histological diagnosis by a comparison of normal human cheek mucosa and cheek mucosa affected by lichen planus.

As an example of the use of quantitation in histological diagnosis the features of normal human cheek mucosa (NHCM) and non-ulcerative lichen planus of the cheek mucosa (LPCM) have been systematically studied and quantified in order to establish normal and pathological features which are constant. The technique enabled the quantitative verification of previously held concepts relating to NHCM and LPCM. A number of interesting features which have been given little attention in past literature were also noted. It is proposed that a reliable quantifiable range of characteristic histological features should be established for use in diagnosis where possible rather than relying on the subjective approach currently employed.