Медицинская библиотека · Wei sheng yan jiu = Journal of hygiene research · 2015

[Association between polymorphisms in the human dopamine D3 receptor gene and genetic susceptibility of essential tremor].

Wang Feng, Zhao Zhong

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Аннотация

OBJECTIVE

To study the association between polymorphisms in the human dopamine D3 receptor ( DRD3 ) gene and genetic susceptibility of essential tremor in different groups.

METHODS

The DRD3 gene polymorphism in ET and health control groups were analyzed with MscI restricted fragment length polymorphism ( RFLP). The results of PCR-RFLP were analyzed by using the statistical software.

RESULTS

No significant differences in alleles and allele frequency of MscI site at the DRD3 gene locus were observed between healthy control and different ET groups.

CONCLUSION

There is no association between polymorphisms MscI site at DRD3 and genetic susceptibility of ET.

Для цитирования: Wang Feng, Zhao Zhong. [Association between polymorphisms in the human dopamine D3 receptor gene and genetic susceptibility of essential tremor].. Wei sheng yan jiu = Journal of hygiene research. 2015.

Предметные рубрики MeSH

Alleles Case-Control Studies Essential Tremor Gene Frequency Genetic Predisposition to Disease Genotype Humans Polymerase Chain Reaction Polymorphism, Genetic Polymorphism, Restriction Fragment Length Receptors, Dopamine D2 Receptors, Dopamine D3

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