Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology · 2005
[Expression and distribution of aquaporin-5 in human nasal polyps].
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Li Zhihai, Gao Qixue
Аннотация
OBJECTIVE: To investigate the distribution and expression of aquaporin-5 (AQP-5) in nasal polyps and explore the role of AQP-5 in the formation of nasal polyps and the normal function of AQP-5 in the inferior turbinate.
METHOD: AQP-5 were studied in 30 samples nasal polyps and 12 samples of inferior turbinates with immunochemistric staing.
RESULT: The level of AQP-5 positive cells in the serous cells from nasal polyps were lesser than that from inferior turbinate, and the level of AQP-5 positive cells in the blood vessel endothelium from nasal polyps were more than that from inferior turbinate.
CONCLUSION: AQP-5 may play the role in both the formation of nasal polyps and the function of normal nasal mucous membrane.
METHOD: AQP-5 were studied in 30 samples nasal polyps and 12 samples of inferior turbinates with immunochemistric staing.
RESULT: The level of AQP-5 positive cells in the serous cells from nasal polyps were lesser than that from inferior turbinate, and the level of AQP-5 positive cells in the blood vessel endothelium from nasal polyps were more than that from inferior turbinate.
CONCLUSION: AQP-5 may play the role in both the formation of nasal polyps and the function of normal nasal mucous membrane.