[Functional sequelae and clinical importance of atrophic duodenitis].

As compared to healthy persons and patients with non-atrophic duodenitis, patients with atrophic duodenitis manifest a decrease of gallbladder contractility as shown by the ultrasonography data. In chronic pancreatitis with concomitant atrophic duodenitis, the degree of a decrease in pancreatic enzymic secretion is more considerable than in patients suffering from chronic pancreatitis without duodenitis or from non-atrophic duodenitis. Comparison of the tests for enhancement of the incretion of endogenous cholecystokinin-pancreozymin and with intravenous injection of the hormone formed the basis for regarding incretory duodenal insufficiency as a cause of hypomotor dyskinesia of the gallbladder and deepening of pancreatic enzymic secretion inhibition in cases with atrophic duodenitis. The data obtained may be of importance for estimating the mechanisms of the impairment of gallbladder contractility and pancreatic enzymic secretion in alimentary diseases as well as for prognosis determination and choice of therapeutic modalities.