Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology · 2026
Fecal incontinence among patients with ulcerative colitis and relation with disease activity, and extent: A cross-sectional study.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Hanayama Masakazu, Furukawa Shinya, Miyake Teruki, Yoshida Osamu, Shiraishi Kana, Tange Kazuhiro, Hashimoto Yu, Suzuki Seiyuu, Ohashi Katsuhisa, Tomida Hideomi, Yamamoto Yasunori, Takeshita Eiji, Ikeda Yoshio, Hiasa Yoichi
Аннотация
BACKGROUND AND STUDY AIMS: Fecal incontinence reduces patients' quality of life. However, evidence regarding fecal incontinence in ulcerative colitis is limited.
PATIENTS AND METHODS: To cross-sectionally examine disease activity, disease extent, the combination of disease activity and disease extent, along with fecal incontinence in ulcerative colitis. Fecal incontinence and severe fecal incontinence were defined on the basis of the frequency of incontinence obtained using a self-administered questionnaire. Complete mucosal healing and mucosal healing were defined as Mayo endoscopic subscores of 0 and 1, respectively. Information on clinical remission and disease extent was collected from the medical records.
RESULTS: This study included 290 ulcerative colitis patients (mean age: 50.3 ± 16.0 years). Disease extents were 119, 80, 84, and 7 cases of total colitis, left-sided colitis, proctitis, and others, respectively. The rates of male sex, complete mucosal healing (CMH), mucosal healing (MH), clinical remission (CR), fecal incontinence, and severe fecal incontinence were 57.6%, 25.2%, 61.0%, 59.3%, 13.8%, and 5.9%, respectively. CMH, MH, and CR were independently inversely associated with fecal incontinence and severe fecal incontinence, respectively. During the active stage of total colitis in ulcerative colitis there was an independent and positive association with fecal incontinence and severe fecal incontinence (adjusted OR 2.51 [95% CI 1.22-5.18], and adjusted OR 3.95 [95% CI 1.38-11.85]). Other disease extents were not associated with fecal incontinence or severe fecal incontinence, regardless of active stage.
CONCLUSIONS: In ulcerative colitis, disease activity was independently inversely associated with fecal incontinence. The total colitis with active stage was significantly positively associated with fecal incontinence.
PATIENTS AND METHODS: To cross-sectionally examine disease activity, disease extent, the combination of disease activity and disease extent, along with fecal incontinence in ulcerative colitis. Fecal incontinence and severe fecal incontinence were defined on the basis of the frequency of incontinence obtained using a self-administered questionnaire. Complete mucosal healing and mucosal healing were defined as Mayo endoscopic subscores of 0 and 1, respectively. Information on clinical remission and disease extent was collected from the medical records.
RESULTS: This study included 290 ulcerative colitis patients (mean age: 50.3 ± 16.0 years). Disease extents were 119, 80, 84, and 7 cases of total colitis, left-sided colitis, proctitis, and others, respectively. The rates of male sex, complete mucosal healing (CMH), mucosal healing (MH), clinical remission (CR), fecal incontinence, and severe fecal incontinence were 57.6%, 25.2%, 61.0%, 59.3%, 13.8%, and 5.9%, respectively. CMH, MH, and CR were independently inversely associated with fecal incontinence and severe fecal incontinence, respectively. During the active stage of total colitis in ulcerative colitis there was an independent and positive association with fecal incontinence and severe fecal incontinence (adjusted OR 2.51 [95% CI 1.22-5.18], and adjusted OR 3.95 [95% CI 1.38-11.85]). Other disease extents were not associated with fecal incontinence or severe fecal incontinence, regardless of active stage.
CONCLUSIONS: In ulcerative colitis, disease activity was independently inversely associated with fecal incontinence. The total colitis with active stage was significantly positively associated with fecal incontinence.