International journal of surgery case reports · 2026
A rare case of multifocal prostatic blue nevus: a case report.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Kalantari Mahmoud Reza, Aslzare Mohammad, Karimi Mohadeseh, Mashoufi Ramin, Ghorbanzadeh Amirhossein, Ramezani Farzaneh
Аннотация
INTRODUCTION AND IMPORTANCE: Prostatic blue nevus (PBN) is an exceptionally rare benign melanocytic lesion of the prostate, usually discovered incidentally.
CASE PRESENTATION: A 59-year-old Iranian male in otherwise good health presented to a urology clinic with an elevated PSA of 5.8 and obstructive symptoms. Digital rectal examination was normal. Trans-rectal ultrasound-guided biopsy revealed blue nevus in 4 out of 12 cores. Histology showed pigmented spindle cells in stroma confirmed by Fontana-Masson stain. Immunohistochemistry was positive for S100, HMB45, and Melan-A. No malignancy was seen.
CLINICAL DISCUSSION: Blue nevus may be confused with malignant melanoma, especially in the absence of clinical suspicion. Immunohistochemistry plays a vital role in differentiation. The lesion has excellent prognosis and requires no follow-up beyond routine screening.
CONCLUSION: We present a case of multifocal PBN identified during evaluation for lower urinary tract symptoms. Awareness of this entity is crucial to avoid misdiagnosis and unnecessary interventions.
CASE PRESENTATION: A 59-year-old Iranian male in otherwise good health presented to a urology clinic with an elevated PSA of 5.8 and obstructive symptoms. Digital rectal examination was normal. Trans-rectal ultrasound-guided biopsy revealed blue nevus in 4 out of 12 cores. Histology showed pigmented spindle cells in stroma confirmed by Fontana-Masson stain. Immunohistochemistry was positive for S100, HMB45, and Melan-A. No malignancy was seen.
CLINICAL DISCUSSION: Blue nevus may be confused with malignant melanoma, especially in the absence of clinical suspicion. Immunohistochemistry plays a vital role in differentiation. The lesion has excellent prognosis and requires no follow-up beyond routine screening.
CONCLUSION: We present a case of multifocal PBN identified during evaluation for lower urinary tract symptoms. Awareness of this entity is crucial to avoid misdiagnosis and unnecessary interventions.