Frontiers in oncology · 2026
Primary vaginal yolk sac tumor in an 11-month-old girl: a case report.
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You Jiacheng, Xia Wei
Аннотация
BACKGROUND: Extragonadal yolk sac tumors are exceedingly rare. This report describes a vaginal yolk sac tumor in an infant to highlight key diagnostic and therapeutic aspects and its inclusion in the differential diagnoses of unexplained vaginal masses.
CASE PRESENTATION: An 11-month-old girl presented with intermittent vaginal bleeding, initially misdiagnosed as a hematoma. Pathological examination confirmed yolk sac tumors. She underwent hysteroscopic resection and six cycles of PEB (bleomycin, etoposide, cisplatin) chemotherapy. No recurrence occurred during the 12-month follow-up.
CONCLUSION: Primary vaginal yolk sac tumors are extremely rare and lack standardized treatment. Surgery combined with PEB chemotherapy proved effective in this case.
CASE PRESENTATION: An 11-month-old girl presented with intermittent vaginal bleeding, initially misdiagnosed as a hematoma. Pathological examination confirmed yolk sac tumors. She underwent hysteroscopic resection and six cycles of PEB (bleomycin, etoposide, cisplatin) chemotherapy. No recurrence occurred during the 12-month follow-up.
CONCLUSION: Primary vaginal yolk sac tumors are extremely rare and lack standardized treatment. Surgery combined with PEB chemotherapy proved effective in this case.