[Effect of surgical and combined treatments on the state of the blood coagulating system in cancer of the corpus uteri].

The study of blood coagulability in the coarse of combination (77 cases) and surgical (17 cases) treatment of endometrial carcinoma showed that surgery is followed by an increased plasma tolerance to heparin, a raised fibrinogen level and a lowered fibrinolytic activity. Therefore, surgery promotes blood coagulability, thus increasing the risk of thromboembolic complications in endometrial cancer patients in postoperative period. Preoperative hormonotherapy seems to contribute to this risk since it increases blood coagulability and delays its normalization in postoperative period.