Colonic histoplasmosis in acquired immunodeficiency syndrome mimicking carcinoma.

Four cases of colonic histoplasmosis in patients with acquired immunodeficiency syndrome mimicking other diseases, primarily colonic adenocarcinoma, are presented. This topic has been extensively discussed from the medical and radiologic standpoint, but very few publications are found in the pathology literature. Emphasis is made on the discussion of the clinical manifestations; endoscopic, radiologic, and pathologic characteristics; differential diagnosis; and treatment.