Journal of cardiology cases · 2022
Detection of macrophages engulfing cholesterol crystals and docosahexaenoic acid from spontaneous ruptured aortic plaque.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Noda Hirotaka, Yutani Chikao, Zaima Nobuhiro, Komatsu Sei, Iwa Nobuzo, Takahashi Satoru, Takewa Mitsuhiko, Ohara Tomoki, Kodama Kazuhisa
Аннотация
UNLABELLED: We visualized macrophages engulfing cholesterol crystals from spontaneously ruptured aortic plaques sampled by angioscopy. Docosahexaenoic acid cholesterol ester (DHA-CE) was demonstrated by imaging mass spectrometry. DHA-CE is reported to be produced by macrophages against inflammation. Activities of macrophages against atherosclerosis inside plaques was shown from spontaneously ruptured aortic plaques in situ.
LEARNING OBJECTIVES: Activities of macrophages such as engulfing cholesterol crystals and producing docosahexaenoic acid cholesterol ester were shown from spontaneously ruptured aortic plaques in situ.
LEARNING OBJECTIVES: Activities of macrophages such as engulfing cholesterol crystals and producing docosahexaenoic acid cholesterol ester were shown from spontaneously ruptured aortic plaques in situ.