Annals of vascular surgery · 2025
Recruitment Feasibility of Patients with Peripheral Arterial Disease for a Multidisciplinary Intervention: Findings from the TEAM-PAD Trial.
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Chimoriya Ritesh, James Sophie, Kritharides Leonard, Sen Shaundeep, Behdasht Samim, Suryawanshi Avinash, Davie Huw, Thillainadesan Janani, Elias Nadine, Aitken Sarah Joy
Аннотация
BACKGROUND: Peripheral arterial disease (PAD) is a chronic progressive vascular condition with high morbidity and mortality, often necessitating comprehensive management to mitigate cardiovascular risk. This study assessed the feasibility of recruiting patients with PAD for a multidisciplinary team (MDT)-based care intervention, comparing its effectiveness to standard care within a clinical trial setting.
METHODS: This study was conducted as a cross-sectional analysis nested within the ongoing TEAM-PAD trial and targeted the recruitment of 30 patients within 12 weeks and evaluated recruitment, consent, and retention rates to assess feasibility.
RESULTS: A total of 30 participants were consented within 11 weeks, with an overall recruitment rate of 36.4% and retention rate of 90%. Baseline characteristics were balanced between groups. Participants had a mean age of 68.9 years and a high prevalence of comorbidities. The mean 10-year cardiovascular risk (SMART-REACH) was 42.8%. In the intervention group, implementing MDT recommendations is projected to reduce this risk by 12.1%.
CONCLUSION: Recruitment of patients with PAD into an MDT intervention was feasible and timely, with strong retention and well-balanced baseline characteristics. Although modeled estimates suggest a potential benefit from MDT recommendations, these findings are preliminary and based on a small interim cohort. Evaluation of clinical effectiveness within the larger ongoing randomized controlled trial is needed to evaluate the medium- and long-term impacts of integrated vascular care.
METHODS: This study was conducted as a cross-sectional analysis nested within the ongoing TEAM-PAD trial and targeted the recruitment of 30 patients within 12 weeks and evaluated recruitment, consent, and retention rates to assess feasibility.
RESULTS: A total of 30 participants were consented within 11 weeks, with an overall recruitment rate of 36.4% and retention rate of 90%. Baseline characteristics were balanced between groups. Participants had a mean age of 68.9 years and a high prevalence of comorbidities. The mean 10-year cardiovascular risk (SMART-REACH) was 42.8%. In the intervention group, implementing MDT recommendations is projected to reduce this risk by 12.1%.
CONCLUSION: Recruitment of patients with PAD into an MDT intervention was feasible and timely, with strong retention and well-balanced baseline characteristics. Although modeled estimates suggest a potential benefit from MDT recommendations, these findings are preliminary and based on a small interim cohort. Evaluation of clinical effectiveness within the larger ongoing randomized controlled trial is needed to evaluate the medium- and long-term impacts of integrated vascular care.