Vestnik oftalmologii · 2011
[The effect of parenteral citicoline on visual functions and life quality of patients with primary open-angle glaucoma].
Аннотация на английскомСтатьяНазвание и аннотация: Оригинал на русском
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Frolov M A, Gonchar P A, Barashkov V I, Kumar V, Morozova N S, Frolov A M, Kazakova K A
Аннотация
The effect of nootropic drug citicoline on visual functions, perimetric indexes of static automated perimetry, morphometric characteristics of retinal tomography and life quality of patients with primary open-angle glaucoma (POAG) stage I-III and normalized intraocular pressure (IOP) was studied. 40 patients aged 46-78 years old with POAG stage I-III and normalized IOP were treated with citicoline. Among them there were 24 female and 16 male. The patients were divided into 2 equal groups--experimental and control. Patients of both groups were treated with intravenous citicoline for 10 days. The dose of citicoline in experimental group was 1000 mg/day, in control--500 mg/day. After treatment in both groups visual functions, perimetric indexes of static automated perimetry, morphometric characteristics of retinal tomography and life quality showed improvement. Citicoline has significant neuroprotective effect preventing apoptosis.