Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego · 2005
[The value of plasma interleukin-6 and interleukin-8 in monitoring of patients with breast cancer].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Zakrzewska Irena, Omyła Jacek
Аннотация
The aim of this study was to determine IL-6 and IL-8 in plasma 29 patients with breast cancer in order to evaluate of interleukins in monitoring therapy. These patients were divided into 3 groups. I-control group comprised 25 healthy persons. Group II comprised 14 patients with recently recognized breast cancer. They underwent examination 5 times: before operation, during treatment and follow-up. Group III comprised 15 patients with recurrence cancer. These patients were examined before and after chemotherapy. Before treatment plasma concentration of the IL-6 were increased in 62% and IL-8 in 86% patients. The concentration of IL-6 and IL-8 decreased to normal limits in all patients with remission. In of patients with progressive disease the IL-6 and IL-8 levels decreased during therapy and next rise. The current observations demonstrate that measurements of IL-6 and IL-8 appear to be useful for the evaluation of therapy and monitoring of patients.