Methods in molecular biology (Clifton, N.J.) · 2022
Animal Models of COVID-19: Nonhuman Primates.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Singh Dhiraj K, Cole Journey, Escobedo Ruby A, Alfson Kendra J, Singh Bindu, Lee Tae-Hyung, Alvarez Xavier, Ganatra Shashank R, Carrion Ricardo, Kaushal Deepak
Аннотация
With the advent of the novel SARS-CoV-2, the entire world has been thrown into chaos with severe disruptions from a normal life. While the entire world was going chaotic, the researchers throughout the world were struggling to contribute to the best of their capabilities to advance the understanding of this new pandemic and fast track the development of novel therapeutics and vaccines. While various animal models have helped a lot to understand the basic physiology, nonhman primates have been promising and much more successful in modelling human diseases compared to other available clinical models. Here we describe the different aspects of modelling the SARS-CoV-2 infection in NHPs along with the associated methods used in NHP immunology.