Gastroenterology research and practice · 2018
Long Time from Diagnosis to Surgery May Increase Postoperative Complication Rates in Elective CD Intestinal Resections: An Observational Study.
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Kotze Paulo Gustavo, Magro Daniela Oliveira, Martinez Carlos Augusto Real, Spinelli Antonino, Yamamoto Takayuki, Warusavitarne Janindra, Coy Claudio Saddy Rodrigues
Аннотация
BACKGROUND: There is lack of data analyzing short-term postoperative complications and time from diagnosis to surgery in Crohn's disease (CD).
AIM: To compare complication rates after elective abdominal operations in CD patients with different durations of disease.
METHODS: Retrospective observational study with CD patients who submitted to elective intestinal resections. Patients were allocated in 2 groups according to time to surgery (TS) in less or more than 5 years. Short-term postoperative complications were analyzed and compared between the 2 groups, and binary logistic regression analysis was performed to check for significant variables.
RESULTS: 123 patients were finally included, 77 with TS > 5 years (62.6%) and 46 with TS < 5 years (37.4%). Patients with TS > 5 years had higher rates of overall surgical complications (p = 0.011), reoperations (p = 0.003), surgical site infections (p = 0.014), anastomotic dehiscence (p = 0.021), abdominal abscesses (p = 0.021), and overall medical complications (p = 0.019). On logistic regression, the single significant variable was the confection of stomas (OR: 3.203; 95% CI: 1.011-10.151; p = 0.048).
CONCLUSIONS: Patients with longer time to surgery showed a significant increase in overall medical and surgical postoperative early complications after elective intestinal resections.
AIM: To compare complication rates after elective abdominal operations in CD patients with different durations of disease.
METHODS: Retrospective observational study with CD patients who submitted to elective intestinal resections. Patients were allocated in 2 groups according to time to surgery (TS) in less or more than 5 years. Short-term postoperative complications were analyzed and compared between the 2 groups, and binary logistic regression analysis was performed to check for significant variables.
RESULTS: 123 patients were finally included, 77 with TS > 5 years (62.6%) and 46 with TS < 5 years (37.4%). Patients with TS > 5 years had higher rates of overall surgical complications (p = 0.011), reoperations (p = 0.003), surgical site infections (p = 0.014), anastomotic dehiscence (p = 0.021), abdominal abscesses (p = 0.021), and overall medical complications (p = 0.019). On logistic regression, the single significant variable was the confection of stomas (OR: 3.203; 95% CI: 1.011-10.151; p = 0.048).
CONCLUSIONS: Patients with longer time to surgery showed a significant increase in overall medical and surgical postoperative early complications after elective intestinal resections.