Applications of Fundus-Tracked Perimetry in the Assessment of Visual Sensitivity.

Fundus-tracked perimetry, also called microperimetry, is increasingly used as an outcome measure in retinal gene therapy clinical trials. By combining static automated perimetry and real-time fundus tracking, fundus-tracked perimetry enables accurate assessment of visual sensitivity in the central retina to precisely identify areas of impaired or preserved function.This chapter describes the clinical methods used to perform fundus-tracked perimetry and strategies to improve the reliability of fundus-tracked perimetry measurements, including operator training, patient preparation, and test monitoring.