Acta dermato-venereologica · 2018
The Role of Therapy in Impairing Quality of Life in Dermatological Patients: A Multinational Study.
СтатьяМногоцентровое исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Balieva Flora N, Finlay Andrew Y, Kupfer Jörg, Aragones Lucía Tomas, Lien Lars, Gieler Uwe, Poot Françoise, Jemec Gregor B E, Misery Laurent, Kemeny Lajos, Sampogna Francesca, van Middendorp Henriët, Halvorsen Jon Anders, Ternowitz Thomas, Szepietowski Jacek C, Potekaev Nikolay, Marron Servando E, Altunay Ilknur K, Salek Sam S, Dalgard Florence J
Аннотация
Skin disease and its therapy affect health-related quality of life (HRQoL). The aim of this study was to measure the burden caused by dermatological therapy in 3,846 patients from 13 European countries. Adult outpatients completed questionnaires, including the Dermatology Life Quality Index (DLQI), which has a therapy impact question. Therapy issues were reported by a majority of patients with atopic dermatitis (63.4%), psoriasis (60.7%), prurigo (54.4%), hidradenitis suppurativa (54.3%) and blistering conditions (53%). The largest reduction in HRQoL attributable to therapy, as a percentage of total DLQI, adjusted for confounders, was seen in blistering conditions (10.7%), allergic/drug reactions (10.2%), psoriasis (9.9%), vasculitis/immunological ulcers (8.8%), atopic dermatitis (8.7%), and venous leg ulcers (8.5%). In skin cancer, although it had less impact on HRQoL, the reduction due to therapy was 6.8%. Treatment for skin disease contributes considerably to reducing HRQoL: the burden of dermatological treatment should be considered when planning therapy and designing new dermatological therapies.