Transplantation proceedings · 2022
Autoimmune Hepatitis in an Immunosuppression-Free Patient Who Underwent Living Donor Liver Transplantation From an Identical Twin: A Case Report.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Toshida Katsuya, Toshima Takeo, Harada Noboru, Nakayama Yuki, Tomiyama Takahiro, Morinaga Akinari, Kosai-Fujimoto Yukiko, Tomino Takahiro, Kurihara Takeshi, Nagao Yoshihiro, Morita Kazutoyo, Itoh Shinji, Yoshizumi Tomoharu
Аннотация
Although there have been a few liver transplantations (LTs) between identical twins, to our knowledge hepatic damage after LT in an immunosuppressant-free patient has not been reported. Autoimmune liver disease recurrence after LT is also a postoperative problem. In this follow-up to our previous report, we present the case of a 57-year-old man with acute liver failure who underwent living donor liver transplantation (LDLT) from an identical twin. Six months after LDLT, the patient was free from immunosuppressive medication and showed good liver function. However, 1 year after LDLT, he developed liver damage and was diagnosed with autoimmune hepatitis by liver biopsy. His liver function was improved with steroid pulse therapy and the resumption of immunosuppressive medications. Even after LDLT from an identical twin, careful management is required for patients to remain free of immunosuppressive medications, considering the background liver disease.