[Pneumococcal vaccine and influenza vaccine for prevention of exacerbation in patients with COPD].

Patients with chronic obstructive pulmonary diseases (COPD) are frequently exposed to infectious agents including influenza virus and Streptococcus pneumoniae. These infectious agents cause pneumonia and exacerbation of COPD. Prevention as well as anti-microbial treatments is critical for COPD. International guideline recommends that all COPD patients should be vaccinated against influenza virus. While pneumococcal vaccine is recommended for older and severe cases at present. Recently additive effect of pneumococcal vaccine and influenza vaccine are shown.