[Analysis on xTAG RVP testing results of hospitalized patients with suspected viral pneumonia].

OBJECTIVE

To analyze the testing results of hospitalized patients with suspected viral pneumonia using xTAG Respiratory Virus Panel Array (xTAG RVP).

METHODS

133 hospitalized patients with suspected viral pneumonia from Peking Union Medical College Hospital from January 2013 to December 2014 were divided into two groups, including 42 young and middle-aged patients (17-49 years old) and 91 middle and old-aged patients (50-88 years old). The nucleic acids of sputum or bronchoalveolar lavage fluid (BALF) samples from the two group patients were screened by xTAG RVP and the results were analyzed.

RESULTS

Viruses can be detected from 50 out of all 133 samples, and the positive rate was 37.6%. Among the viral positive samples, the proportion of mixed infections was 12.0%. The detection rates of Influenza A virus (FluA) and Rhinovirus (RV) were higher than others (45.0% and 16.7%). The infection rate of young and middle-aged patients was significantly higher than that of the middle and old-aged patients (73.8% vs 31.9%, P<0.001). The viral detection rates of samples from spring, summer, autumn and winter were 25.0%, 6.7%, 20.0% and 38.3%, respectively. The positive rate difference among four seasons was not significant (P=0.257).

CONCLUSION

FluA and RV are dominant respiratory viruses in hospitalized patients with suspected viral pneumonia, and the infection rate of the young and middle-aged patients is higher than the middle and old-aged patients.