Comparison of the Patient-Reported Outcome Measure for Vascular Malformation and Outcome Measures for Vascular Malformation Questionnaires: A Prospective Cohort Study.

The Patient-Reported Outcome Measure for Vascular Malformation (PROVAM) and the Outcome Measures for Vascular Malformation (OVAMA) are validated tools to assess health-related quality of life (HRQoL) in patients with vascular malformations (VMs). This prospective study compared PROVAM and OVAMA across 250 patient responses to evaluate measure comprehensiveness and patient preferences. Among respondents, 165 (66.0%) reported pain. Those with pain significantly favored the PROVAM questionnaire (58.4%), whereas those without pain preferred OVAMA (68.9%; χ²=11.93, P=<0.001). Anatomical location also influenced preferences: patients with trunk or extremity VMs favored PROVAM (35%) or showed no preference (38.8%), whereas those with a head/neck VM favored OVAMA (45.9%; χ²=11.09, P=<0.001). These findings suggest that patient characteristics, such as the presence of pain and VM location, influence PROM preference. PROVAM's focus on functional impact aligns with the needs of patients experiencing pain, while OVAMA's emphasis on physical symptoms and appearance may be more relevant to those without pain. Tailoring patient-reported outcome measure selection may improve HRQoL assessment and patient-centered care.