Impact of targeted nursing care and nutritional support on clinical outcomes in diabetic nephropathy patients undergoing maintenance hemodialysis.

This study aimed to investigate the impact of targeted nursing care combined with nutritional support on the clinical outcomes of diabetic nephropathy (DN) patients undergoing maintenance hemodialysis (HD). Clinical indicators such as serum creatinine (SCr), blood urea nitrogen (BUN), fasting blood glucose (FBG), hemoglobin A1c (HbA1c), and K (urea clearance) × t (dialysis time) / V (volume of urea distribution) (Kt/V), as well as inflammatory indicators such as high-sensitivity C-reactive protein (hs-CRP), interleukin (IL)-6, and tumor necrosis factor-α (TNF-α), and nutritional indicators such as transferrin (TRF), albumin (ALB), and prealbumin (PA) were measured. SF-36 quality of life scale scores were assessed, and adverse events and patient satisfaction with care were recorded. Post-intervention, the experimental group exhibited lower SCr, BUN, FBG, HbA1c, hs-CRP, IL-6, and TNF-α, and higher body mass index, Kt/V, TRF, ALB, and PA than the control group (all P<0.05). Additionally, the experimental group demonstrated higher nursing satisfaction scores, and lower total incidence of adverse events compared to the control group (all P<0.05). Targeted nursing care combined with nutritional support applied to DN patients during HD helped improve residual renal function, reduce the body's inflammatory response, improve nutritional status and the quality of life, reduce adverse events, and at the same time, improve nursing satisfaction.