Indian pediatrics · 2021
Serum IgG Titers Against Toxoplasma gondii in Uninfected Infants Exposed In Utero to Toxoplasmosis.
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Vivacqua Daniela Pires Ferreira, Frota Ana Cristina Cisne, Martins Mariana Guerreiro, Abreu Thalita Fernandes, Hofer Cristina Barroso
Аннотация
OBJECTIVES: To describe the mean time of decrease of T. gondii IgG titers in uninfected infants exposed in utero to toxoplasmosis.
METHODS: A retrospective cohort study was conducted between 2008-2017, among infants under 12 months and exposed in utero to toxoplasmosis. Serial monthly monitoring of serum IgG titers were done till undetectable levels.
RESULTS: 240 infants with mean gestational age at diagnosis of 19.2 weeks were included in the study. The mean (range) time for IgG level to become undetectable was 7.9 (0.8-25.0) months. 14 infants became negative between 13-24 months.
CONCLUSIONS: Majority of asymptomatic infants exposed in utero to T. gondii become seronegative before 12 months of age.
METHODS: A retrospective cohort study was conducted between 2008-2017, among infants under 12 months and exposed in utero to toxoplasmosis. Serial monthly monitoring of serum IgG titers were done till undetectable levels.
RESULTS: 240 infants with mean gestational age at diagnosis of 19.2 weeks were included in the study. The mean (range) time for IgG level to become undetectable was 7.9 (0.8-25.0) months. 14 infants became negative between 13-24 months.
CONCLUSIONS: Majority of asymptomatic infants exposed in utero to T. gondii become seronegative before 12 months of age.