Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology · 2003
[Preliminary study of correlation factor in surgery effect of nasal polyps].
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Wu Xu, Kong Hui, Zang Yuhua, Wang Lifen
Аннотация
OBJECTIVE: To study the relation between nasal polyp pathology, cellular expression of CD45 RO, CD20, CD68, proliferating cell nuclear antigen (PCNA) in nasal polyps and the response to surgery.
METHOD: Nasal polyp tissues from 50 patients were evaluated for cellular expression of CD45 RO, CD20, CD68, PCNA using immunohistochemistry SP by counting the average number in 5 chosen high-power fields, histopathological observations were combined with clinic and postoperative dates. Analyses were performed on SPSS10.0.
RESULT: Significant correlation was found between CD68+ cells and eosinophils or PCNA positive cells on epithelium. PCNA positive cells on epithelium has significant correlation on fibroblast (P < 0.05). The nasal polyps dominated with CD68+ and high polyp score have significant correlation to cure.
CONCLUSION: Extent of inflammatory cells infiltration especially CD68+ or eosinophilia or lymphocytes and polyp score have significant effect on cure rate.
METHOD: Nasal polyp tissues from 50 patients were evaluated for cellular expression of CD45 RO, CD20, CD68, PCNA using immunohistochemistry SP by counting the average number in 5 chosen high-power fields, histopathological observations were combined with clinic and postoperative dates. Analyses were performed on SPSS10.0.
RESULT: Significant correlation was found between CD68+ cells and eosinophils or PCNA positive cells on epithelium. PCNA positive cells on epithelium has significant correlation on fibroblast (P < 0.05). The nasal polyps dominated with CD68+ and high polyp score have significant correlation to cure.
CONCLUSION: Extent of inflammatory cells infiltration especially CD68+ or eosinophilia or lymphocytes and polyp score have significant effect on cure rate.