Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology · 2003
[Expressions of chloride channel ClC-2 and ClC-3 in human nasal polyps].
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Li Huabin, Han Demin, Zhou Bing, Fan Erzhong, Liu Zhongyan
Аннотация
OBJECTIVE: To investigate the role of chloride channel ClC-2 and ClC-3 in human nasal polyps.
METHOD: Two chloride channels ClC-2 and ClC-3 were studied in 27 cases of nasal polyps with immunochemistric staining.
RESULT: Nasal polyps revealed strong positive staining of ClC-2 and ClC-3, the ClC-2 and ClC-3 proteins localized mainly in epithelial cells, sub-epithelial mucous glands without significant distinction. The number of positive cells of ClC-2 and ClC-3 are 17.6 +/- 6.33 and 23.49 +/- 6.14.
CONCLUSION: The chloride channels ClC-2 and ClC-3 may play a role in the formation of nasal polyps.
METHOD: Two chloride channels ClC-2 and ClC-3 were studied in 27 cases of nasal polyps with immunochemistric staining.
RESULT: Nasal polyps revealed strong positive staining of ClC-2 and ClC-3, the ClC-2 and ClC-3 proteins localized mainly in epithelial cells, sub-epithelial mucous glands without significant distinction. The number of positive cells of ClC-2 and ClC-3 are 17.6 +/- 6.33 and 23.49 +/- 6.14.
CONCLUSION: The chloride channels ClC-2 and ClC-3 may play a role in the formation of nasal polyps.