Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology · 2003
[Expression and significance of vascular permeability factor (VPF) in inflammatory cells of nasal polyps].
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Yang Jihong, Dong Zhen, Gao Jinjian
Аннотация
OBJECTIVE: To study the expression and significance of vascular permeability factor (VPF) in eosinophil, macrophage and plasma cell in nasal polyps.
METHOD: VPF in 12 nasal polyps was studied by immunohistochemistry, double immune-enzymatic staining technique and double MGG staining technique. Each section was observed under optical microscope.
RESULT: Immunohistochemistry result: VPF was detected in the cells showing morphological feature of plasma cells. Double immune-enzymatic staining result: CD68 positive cells in the second staining conformed to VPF positive cells in the first staining. MGG and immune-enzymatic double staining result: eosinophils in MGG staining were in conformity with some VPF positive cells.
CONCLUSION: Positive expression of VPF in eosinophils, macrophages and plasma cells indicates that VPF may play a role in the formation of heavy edema of nasal polyps.
METHOD: VPF in 12 nasal polyps was studied by immunohistochemistry, double immune-enzymatic staining technique and double MGG staining technique. Each section was observed under optical microscope.
RESULT: Immunohistochemistry result: VPF was detected in the cells showing morphological feature of plasma cells. Double immune-enzymatic staining result: CD68 positive cells in the second staining conformed to VPF positive cells in the first staining. MGG and immune-enzymatic double staining result: eosinophils in MGG staining were in conformity with some VPF positive cells.
CONCLUSION: Positive expression of VPF in eosinophils, macrophages and plasma cells indicates that VPF may play a role in the formation of heavy edema of nasal polyps.