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Медицинская библиотека · Investigacion clinica · 2005

[Superficial mycoses: comparative study between type 2 diabetic patients and a non-diabetic control group].

García-Humbría Leila, Richard-Yegres Nicole, Pérez-Blanco Maigualida, Yegres Francisco, Mendoza Mireya, Acosta Arnaldo, Hernández Rosaura, Zárraga Eluz

Сравнительное исследованиеАннотация на английскомСтатьяПоддержка исследования: вне правительства СШАПеревод в очереди

Аннотация

Superficial mycoses are considered to affect more frequently patients with type 2 diabetes mellitus (DM-2), specially onychomycosis and Tinea pedis. The purpose of this study was to compare the dermatophytoses, candidiasis and Pitiriasis versicolor frequency between 40 patients with DM-2 and 40 healthy persons of either sex, 40 years old or more. Clinical, metabolic, mycologic and inmunologic studies against Candida albicans, were carried out. Both diabetics 75% (30/40) and controls 65% (26/40) presented a high frequency of superficial mycoses (no significant difference p = 0.329). Pitiriasis versicolor was not detected in diabetic patients. They presented Tinea unguium, concomitant with Tinea pedis, with a higher frequency. The predominant dermatophyte was Trichophyton rubrum 18/23 (78%) in diabetics and 8/16 (50%) in non diabetics. Candida was isolated as commensal from oral mucous: 23/40 (58%) in diabetics and 21/40 (52%) in non diabetics (serotipo A was the more frequent), and from onychomycosis: 11/40 (28%) in diabetics and 12/40 (30%) in non diabetics. The immunological response was the same in both groups: celular 100%, humoral 20%. No statistical correlation among superficial mycoses, blood glucose level, glycosylated hemoglobin values or the time suffering the disease was observed. The high susceptibility to dermatophytes and Candida sp. infection showed to be associated with age and no with the diabetic type 2 condition in those patients.

Для цитирования: García-Humbría Leila, Richard-Yegres Nicole, Pérez-Blanco Maigualida, Yegres Francisco, Mendoza Mireya, Acosta Arnaldo, Hernández Rosaura, Zárraga Eluz. [Superficial mycoses: comparative study between type 2 diabetic patients and a non-diabetic control group].. Investigacion clinica. 2005.

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