Wiadomosci lekarskie (Warsaw, Poland : 1960) · 2025
Association of soluble vascular cell adhesion molecule -1 (sVACAM-1) with cardiovascular disease and glycemic control among type 2 diabetic patients.
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Kadhim Iman Jabbar, Rasheed Suaad Muhammed, Deli Falah Abdulhasan, Alfadhul Shaymaa Abdullateef
Аннотация
OBJECTIVE: Aim: This study aimed to assess the Association of sVACAM-1 with type 2 diabetes mellitus and the impact of cardiovascular disease and glycemic control on its level.
PATIENTS AND METHODS: Materials and Methods: This is a study of sVACAM-1 level in 57 patients with type 2 Diabetes mellitus in Al-Najaf/Iraq in comparison with normal control, the level of sVACAM-1 was analyzed also according to parameters of age, sex, smoking, body mass index (BMI), presence of systemic hypertension and cardiovascular diseases (ischemic heart disease and heart failure), Poor diabetic control (Hemoglobin A1C ≥7) and the mean of 2 days postprandial blood sugar.
RESULTS: Results: All parameters except smoking were associated with higher levels of sVACAM-1, however the differences weren't significant statistically, there was no linear correlation between the mean 2 days post prandial blood sugar and sVACAM-1.
CONCLUSION: Conclusions: sVACAM-1 is important to be assessed in diabetic patients and recommended to establish cutoff values of normality.
PATIENTS AND METHODS: Materials and Methods: This is a study of sVACAM-1 level in 57 patients with type 2 Diabetes mellitus in Al-Najaf/Iraq in comparison with normal control, the level of sVACAM-1 was analyzed also according to parameters of age, sex, smoking, body mass index (BMI), presence of systemic hypertension and cardiovascular diseases (ischemic heart disease and heart failure), Poor diabetic control (Hemoglobin A1C ≥7) and the mean of 2 days postprandial blood sugar.
RESULTS: Results: All parameters except smoking were associated with higher levels of sVACAM-1, however the differences weren't significant statistically, there was no linear correlation between the mean 2 days post prandial blood sugar and sVACAM-1.
CONCLUSION: Conclusions: sVACAM-1 is important to be assessed in diabetic patients and recommended to establish cutoff values of normality.