mLife · 2025
Phage therapy of perinephric abscess in kidney transplantation recipients caused by drug-resistant Pseudomonas aeruginosa.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Liu Jiazhen, Lu Shuguang, Bao Juan, Wang Jing, Gong Yali, He Bo, Zhu Yuhao, Zhong Zhuojun, Li Shiru, Li Linlin, Li Na, Cheng Mengjun, Li Ming, Shen Mengyu, Wu Nannan, Zhu Tongyu, Le Shuai
Аннотация
Perinephric abscess, a common complication after kidney transplantation, often results from drug-resistant bacterial infections and is notoriously difficult to treat. Phage therapy has emerged as a promising alternative for such resistant infections. Here, we present two cases of perinephric abscesses in kidney transplant recipients (KTRs) treated with phage therapy. Our findings highlight the need for personalized treatment plans and timely intervention with phage therapy to improve patient outcomes. Future research should focus on overcoming barriers like biofilms to make this treatment more effective. Ultimately, phage therapy could lead to better survival rates and improved quality of life for transplant patients facing severe infections. This study is a step forward in the fight against superbugs, offering a potential alternative when antibiotics fail.