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DOI 10.18632/oncotarget.23262

Медицинская библиотека · Oncotarget · 2017

MiR-27a as a predictor for the activation of hepatic stellate cells and hepatitis B virus-induced liver cirrhosis.

Zhang Hui, Yan Xiu-Li, Guo Xin-Xin, Shi Miao-Juan, Lu Yi-Yu, Zhou Qian-Mei, Chen Qi-Long, Hu Yi-Yang, Xu Lie-Ming, Huang Shuang, Su Shi-Bing

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Аннотация

IMPORTANCE

Recent years have seen a shift to strengths-based approaches promoting self-determination and career-related interests among autistic youth. Research is needed to understand the career-related goals set by autistic youth on the basis of their interests.

OBJECTIVE

To descriptively explore the career design goals set by autistic youth engaged in the self-determined career design model (SDCDM) intervention.

DESIGN

Content analysis was used to analyze the types of goals set by youth during intervention. Two researchers separately reviewed the goal set by each autistic youth (one goal per youth) and determined categories for each goal.

SETTING

Preferred community location (usually the youth's home) in an urban Midwestern city.

PARTICIPANTS

Twenty-one autistic youth.

INTERVENTION: SDCDM.

OUTCOMES AND MEASURES: Participants set goals as part of the SDCDM, which were recorded using Goal Attainment Scaling (GAS). Researchers used GAS to support each participant in setting a measurable and objective goal and describing criteria for meeting the goal.

RESULTS

Categories included enhancing self-management, obtaining employment, exploring career opportunities, enhancing learning, and enhancing self-advocacy.

CONCLUSIONS AND RELEVANCE: The findings from this study indicate that autistic youth set goals related to obtaining employment and enhancing generalizable 21st-century skills, such as self-advocacy and self-management. What This Article Adds: The SDCDM is a tool occupational therapy practitioners can use to support youth in setting and working toward career goals.

Для цитирования: Zhang Hui, Yan Xiu-Li, Guo Xin-Xin, Shi Miao-Juan, Lu Yi-Yu, Zhou Qian-Mei, Chen Qi-Long, Hu Yi-Yang, Xu Lie-Ming, Huang Shuang, Su Shi-Bing. MiR-27a as a predictor for the activation of hepatic stellate cells and hepatitis B virus-induced liver cirrhosis.. Oncotarget. 2017. DOI: 10.18632/oncotarget.23262.
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