Glycobiology · 2024
The Human Glycome Atlas project for cataloging all glycan-related omics data in human.
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Aoki-Kinoshita Kiyoko F, Akune-Taylor Yukie, Ando Hiromune, Angata Kiyohiko, Fujita Morihisa, Furukawa Jun-Ichi, Kaji Hiroyuki, Kato Koichi, Kitajima Ken, Kizuka Yasuhiko, Matsui Yusuke, Nakajima Kazuki, Nishihara Shoko, Okajima Tetsuya, Sakamoto Kazuma, Sato Chihiro, Thaysen-Andersen Morten, Togayachi Akira, Yagi Hirokazu, Zappa Achille, Kadomatsu Kenji
Аннотация
The Human Glycome Atlas (HGA) Project was launched in April 2023, spearheaded by three Japanese institutes: the Tokai National Higher Education and Research System, the National Institutes of Natural Sciences, and Soka University. This was the first time that a field in the life sciences was adopted by the Ministry of Education, Culture, Sports, Science and Technology (MEXT) for a Large-scale Academic Frontiers Promotion Project. This project aims to construct a knowledgebase of human glycans and glycoproteins as a standard for the human glycome. A high-throughput pipeline for comprehensively analyzing 20,000 blood samples in its first five years is planned, at which time an access-controlled version of a human glycomics knowledgebase, called TOHSA, will be released. By the end of the final tenth year, TOHSA will provide a central resource linking human glycan data with other omics data including disease-related information.