Impact of biotechnology on trichinellosis control.

The century-old effort to rid Trichinella spiralis from the food supply has had variable success, and in some regions trichinellosis remains a serious public health concern. However, the research advanced during the past 5 years points toward greater success in developing practical and efficient control strategies. The application of monoclonal antibody and recombinant DNA technologies has permitted great improvement in diagnosis and production of diagnostic reagents. Further, the epidemiology of the disease has undergone considerable revision because of the power of DNA analytical technics which are unravelling the complex genetics of Trichinella spiralis. This improved understanding of the parasite's epidemiology is critical to the design of improved control strategies.