The dynamics of eosinophilia in concurrent infections with Trichinella spiralis Owen, 1835 and Toxascaris leonina Linstow, 1909.

The concurrent infection with larvae of Trichinella spiralis and eggs of Toxascaris leonina was studied under various conditions using 75 male white mice. The changes in content of eosinophilic leucocytes in the blood, as well as the total number and distribution of larvae of both parasites in different body tissues were demonstrated. The primary infection with Toxascaris leonina caused an increase in the number of eosinophilic leucocytes from day 4 p.i., whereas the infection with Trichinella spiralis larvae induced an increase only from day 7 p.i. An antagonism was observed between the two parasite species: the primary infection with T. leonina led to a decrease in the total number of muscle larvae of T. spiralis, and, vice versa, the primary infection with T. spiralis suppressed the development of T. leonina.