Effect of vitamins on Trichinella spiralis Owen, 1835 infection in mice.

The effects of vitamins A, B complex, E, and ADE on the body weight, eosinophilia, intensity of infection and distribution of T. spiralis larvae were studied in mice. The greatest loss of weight followed after the application of vitamins B complex and E. An increased eosinophilia appeared in the majority of infected mice since day 7 p.i., reaching the maximum on day 21 p.i. In mice receiving vitamins B complex, A, and ADE, the increased eosinophilia was observed still on day 60 p.i. The highest levels of eosinophilia occurred after the application of vitamins B complex and E, which was directly proportional to the intensity of infection. The lowest intensity of infection was recorded in mice receiving vitamin A. Though there were great differences between individual mice, the greatest number of larvae were localized in the diaphragm and left masseter.