Immune reactions in guinea pigs due to somatic antigens from fourth-stage larvae of Bunostomum trigonocephalum.

Lyophilized somatic antigens obtained from fourth-stage larvae of Bunostomum trigonocephalum induced significant resistance against the development of L4 from L3 and adults from L4. The higher antigen dose (1,000 LE) significantly reduced the number of adults developed from L4 as compared to the lower dose (600 LE) which did so only insignificantly. Inflammation of the intestinal tissue and loosening of the intestinal luminal contents were characteristics of the immunized animals.